Chloroacetyl Chloride Market - Global Industry Analysis 2025 | TMR
Chloroacetyl
chloride is an organic compound used as a building block for several
important chemical reactions. The molecular formula of the chemical is
C2H2Cl2O. Commercially, chloroacetyl chloride is generally manufactured
by reacting chloroacetic acid with thionyl chloride, sulfuryl chloride,
phosphorus trichloride, or phosgene. Chloroacetyl chloride can also be
obtained through the chlorination of acetyl chloride in the presence of
stronger aliphatic acids such as chloroacetic acids, or from sodium
chloroacetate in the presence of chlorinating agents. Chloroacetyl
chloride is generally available in the form of a colorless liquid that
is highly corrosive. On exposure to moist air, it gives out a pungent
odor along with fumes.
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These
fumes are highly toxic if inhaled and are corrosive to metal. The
chemical is bifunctional—the acyl chloride segment readily forms amide
and ester compounds, while the other segment of the molecule forms other
linkages, e.g. with amines. Chloroacetyl chloride is widely used in the
manufacture of pesticides and pharmaceutical intermediates. It is also
used as an intermediate in several important chemical products. However,
implementation of stringent environmental and health regulations is
likely to hamper the chloroacetyl chloride market.
The
use of chloroacetyl chloride as an intermediate in the production of
alachlor and butachlor is the leading application of the chemical. More
than 100 million pounds of chloroacetyl chloride is consumed annually in
the production of alachlor and butachlor. Alachlor is an herbicide from
the chloroacetanilide family, while butachlor is an herbicide from the
acetanilide family. Chloroacetyl chloride is employed as an intermediate
for many syntheses; the most important one is to make adrenaline,
chloroacetic acid esters, and anhydride.
Chloroacetyl
chloride is also used in the synthesis of N-hydrazino
acetyl-sulphonamides and for the chemical modification of poly(glycidyl
methacrylate). In the medicinal field, chloroacetyl chloride is used in
experiments studying the in vitro metabolism of chloroacetamide
herbicides by rat and human liver microsomes. Chloroacetyl chloride can
also be employed to produce derivatives of quinolone that have
antileishmanial activity. It is also employed in the manufacture of
phenacyl chloride, a chemical intermediate that is used as a lachrymator
agent (commonly known as tear gas).
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Rapid
growth in population across the world has necessitated the use of
chemical fertilizers and pesticides in farming in order to increase crop
production and meet the rising demand for food. Rise in demand for
pesticides is expected to boost the demand for chloroacetyl chloride.
Asia Pacific is the key producer of chloroacetyl chloride. Among
countries in the region, China is an important producer of chloroacetyl
chloride. Other vital producers of chloroacetyl chloride in Asia Pacific
are India, Japan, and Indonesia. The U.S. is the one of the prominent
markets for chloroacetyl chloride; demand for chloroacetyl chloride is
high in the country due to the high per acre consumption of pesticides.
Canada is also a large consumer of chloroacetyl chloride based
fertilizers. With chloroacetyl chloride being banned in Europe, the
region is likely to witness sluggish demand for the chemical over the
next decade. Brazil is a vital consumer of the chemical in Latin
America.
Agriculture
accounts for the major share of the market in Brazil in terms of volume
and revenue. Mexico, Colombia, and Chile are the other important
consumers in Latin America. The use of agrochemicals is increasing in
Africa. This is expected to boost the demand for chloroacetyl acid in
the region. Negative public segment regarding the chemical might affect
consumption in the near future. Developed regions such as the U.S.,
Western Europe, and Australia are estimated to be more affected by these
developments due to the popularity of ‘organic farming’ in these
regions.
Key
players operating in the global chloroacetyl chloride market include
Altivia Corporation, CABB GmbH, Daicel Corporation, Chengwu Chenhui
Environmental Protection Technology Co. Ltd, Transpek Industry Limited,
Taixing Shenlong Chemical Co. Ltd., and Shiv Pharmachem Ltd.

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