Chloroacetyl Chloride Market to Record Sturdy Growth by 2025
Chloroacetyl
chloride is an organic compound used as a building block for several
important chemical reactions. The molecular formula of the chemical
is C2H2Cl2O. Commercially, chloroacetyl chloride is generally
manufactured by reacting chloroacetic acid with thionyl chloride,
sulfuryl chloride, phosphorus trichloride, or phosgene. Chloroacetyl
chloride can also be obtained through the chlorination of acetyl
chloride in the presence of stronger aliphatic acids such as
chloroacetic acids, or from sodium chloroacetate in the presence of
chlorinating agents. Chloroacetyl chloride is generally available in
the form of a colorless liquid that is highly corrosive.
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On
exposure to moist air, it gives out a pungent odor along with fumes.
These fumes are highly toxic if inhaled and are corrosive to metal.
The chemical is bifunctional—the acyl chloride segment readily
forms amide and ester compounds, while the other segment of the
molecule forms other linkages, e.g. with amines. Chloroacetyl
chloride is widely used in the manufacture of pesticides and
pharmaceutical intermediates. It is also used as an intermediate in
several important chemical products. However, implementation of
stringent environmental and health regulations is likely to hamper
the chloroacetyl chloride market.
The
use of chloroacetyl chloride as an intermediate in the production of
alachlor and butachlor is the leading application of the chemical.
More than 100 million pounds of chloroacetyl chloride is consumed
annually in the production of alachlor and butachlor. Alachlor is an
herbicide from the chloroacetanilide family, while butachlor is an
herbicide from the acetanilide family. Chloroacetyl chloride is
employed as an intermediate for many syntheses; the most important
one is to make adrenaline, chloroacetic acid esters, and anhydride.
Chloroacetyl chloride is also used in the synthesis of N-hydrazino
acetyl-sulphonamides and for the chemical modification of
poly(glycidyl methacrylate). In the medicinal field, chloroacetyl
chloride is used in experiments studying the in vitro metabolism of
chloroacetamide herbicides by rat and human liver microsomes.
Chloroacetyl chloride can also be employed to produce derivatives of
quinolone that have antileishmanial activity. It is also employed in
the manufacture of phenacyl chloride, a chemical intermediate that is
used as a lachrymator agent (commonly known as tear gas).
Rapid
growth in population across the world has necessitated the use of
chemical fertilizers and pesticides in farming in order to increase
crop production and meet the rising demand for food. Rise in demand
for pesticides is expected to boost the demand for chloroacetyl
chloride. Asia Pacific is the key producer of chloroacetyl chloride.
Among countries in the region, China is an important producer of
chloroacetyl chloride. Other vital producers of chloroacetyl chloride
in Asia Pacific are India, Japan, and Indonesia. The U.S. is the one
of the prominent markets for chloroacetyl chloride; demand for
chloroacetyl chloride is high in the country due to the high per acre
consumption of pesticides. Canada is also a large consumer of
chloroacetyl chloride based fertilizers.
With
chloroacetyl chloride being banned in Europe, the region is likely to
witness sluggish demand for the chemical over the next decade. Brazil
is a vital consumer of the chemical in Latin America. Agriculture
accounts for the major share of the market in Brazil in terms of
volume and revenue. Mexico, Colombia, and Chile are the other
important consumers in Latin America. The use of agrochemicals is
increasing in Africa. This is expected to boost the demand for
chloroacetyl acid in the region. Negative public segment regarding
the chemical might affect consumption in the near future. Developed
regions such as the U.S., Western Europe, and Australia are estimated
to be more affected by these developments due to the popularity of
‘organic farming’ in these regions.
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Key
players operating in the global chloroacetyl chloride market include
Altivia Corporation, CABB GmbH, Daicel Corporation, Chengwu Chenhui
Environmental Protection Technology Co. Ltd, Transpek Industry
Limited, Taixing Shenlong Chemical Co. Ltd., and Shiv Pharmachem Ltd.
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